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Dopamine Transporter Phosphorylation Site Threonine 53 Regulates Substrate Reuptake and Amphetamine-stimulated Efflux

In the central nervous system, levels of extraneuronal dopamine are controlled primarily by the action of the dopamine transporter (DAT). Multiple signaling pathways regulate transport activity, substrate efflux, and other DAT functions through currently unknown mechanisms. DAT is phosphorylated by...

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Detalles Bibliográficos
Autores principales: Foster, James D., Yang, Jae-Won, Moritz, Amy E., ChallaSivaKanaka, Sathyavathi, Smith, Margaret A., Holy, Marion, Wilebski, Kyle, Sitte, Harald H., Vaughan, Roxanne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436161/
https://www.ncbi.nlm.nih.gov/pubmed/22722938
http://dx.doi.org/10.1074/jbc.M112.367706