Dynamin-mediated Nephrin Phosphorylation Regulates Glucose-stimulated Insulin Release in Pancreatic Beta Cells

We have previously demonstrated a role for Nephrin in glucose stimulated insulin release (GSIR). We now hypothesize that Nephrin phosphorylation is required for GSIR and that Dynamin influences Nephrin phosphorylation and function. MIN6-C3 Nephrin-deficient pancreatic beta cells and human islets wer...

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Detalles Bibliográficos
Autores principales: Jeon, Jongmin, Leibiger, Ingo, Moede, Tilo, Walter, Britta, Faul, Christian, Maiguel, Dony, Villarreal, Rodrigo, Guzman, Johanna, Berggren, Per-Olof, Mundel, Peter, Ricordi, Camillo, Merscher-Gomez, Sandra, Fornoni, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436561/
https://www.ncbi.nlm.nih.gov/pubmed/22718751
http://dx.doi.org/10.1074/jbc.M112.389452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436561/
https://www.ncbi.nlm.nih.gov/pubmed/22718751
http://dx.doi.org/10.1074/jbc.M112.389452

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