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A simple theoretical framework for understanding heterogeneous differentiation of CD4(+) T cells

BACKGROUND: CD4(+) T cells have several subsets of functional phenotypes, which play critical yet diverse roles in the immune system. Pathogen-driven differentiation of these subsets of cells is often heterogeneous in terms of the induced phenotypic diversity. In vitro recapitulation of heterogeneou...

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Detalles Bibliográficos
Autores principales: Hong, Tian, Xing, Jianhua, Li, Liwu, Tyson, John J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436737/
https://www.ncbi.nlm.nih.gov/pubmed/22697466
http://dx.doi.org/10.1186/1752-0509-6-66