Biodistribution and elimination kinetics of systemic Stx2 by the Stx2A and Stx2B subunit-specific human monoclonal antibodies in mice

BACKGROUND: Hemolytic uremic syndrome (HUS) leading to acute kidney failure, is a condition linked to the production of primarily Shiga toxin 2 (Stx2) by some E. coli serotypes. We have previously shown that Stx2 A subunit-specific human monoclonal antibody (HuMAb) 5C12, and B subunit-specific HuMAb...

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Detalles Bibliográficos
Autores principales: Sheoran, Abhineet, Jeong, Kwang-il, Mukherjee, Jean, Wiffin, Anthony, Singh, Pradeep, Tzipori, Saul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436740/
https://www.ncbi.nlm.nih.gov/pubmed/22655967
http://dx.doi.org/10.1186/1471-2172-13-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436740/
https://www.ncbi.nlm.nih.gov/pubmed/22655967
http://dx.doi.org/10.1186/1471-2172-13-27

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