Prognostic gene signatures for patient stratification in breast cancer - accuracy, stability and interpretability of gene selection approaches using prior knowledge on protein-protein interactions

BACKGROUND: Stratification of patients according to their clinical prognosis is a desirable goal in cancer treatment in order to achieve a better personalized medicine. Reliable predictions on the basis of gene signatures could support medical doctors on selecting the right therapeutic strategy. How...

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Detalles Bibliográficos
Autores principales: Cun, Yupeng, Fröhlich, Holger FH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436770/
https://www.ncbi.nlm.nih.gov/pubmed/22548963
http://dx.doi.org/10.1186/1471-2105-13-69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436770/
https://www.ncbi.nlm.nih.gov/pubmed/22548963
http://dx.doi.org/10.1186/1471-2105-13-69

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