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Evaluation of the imputation performance of the program IMPUTE in an admixed sample from Mexico City using several model designs

BACKGROUND: We explored the imputation performance of the program IMPUTE in an admixed sample from Mexico City. The following issues were evaluated: (a) the impact of different reference panels (HapMap vs. 1000 Genomes) on imputation; (b) potential differences in imputation performance between singl...

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Detalles Bibliográficos
Autores principales: Krithika, S, Valladares-Salgado, Adán, Peralta, Jesus, La Peña, Jorge Escobedo-de, Kumate-Rodríguez, Jesus, Cruz, Miguel, Parra, Esteban J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436779/
https://www.ncbi.nlm.nih.gov/pubmed/22549150
http://dx.doi.org/10.1186/1755-8794-5-12