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PI3K p110α Isoform-Dependent Rho GTPase Rac1 Activation Mediates H(2)S-Promoted Endothelial Cell Migration via Actin Cytoskeleton Reorganization

Hydrogen sulfide (H(2)S) is now considered as the third gaseotransmitter, however, the signaling pathways that modulate the biomedical effect of H(2)S on endothelial cells are poorly defined. In the present study, we found in human endothelial cells that H(2)S increased cell migration rates and indu...

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Detalles Bibliográficos
Autores principales: Zhang, Li-Jia, Tao, Bei-Bei, Wang, Ming-Jie, Jin, Hui-Ming, Zhu, Yi-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436785/
https://www.ncbi.nlm.nih.gov/pubmed/22970259
http://dx.doi.org/10.1371/journal.pone.0044590