Synergistic Suppression of Early Phase of Adipogenesis by Microsomal PGE Synthase-1 (PTGES1)-Produced PGE(2) and Aldo-Keto Reductase 1B3-Produced PGF(2α)

We recently reported that aldo-keto reductase 1B3-produced prostaglandin (PG) F(2α) suppressed the early phase of adipogenesis. PGE(2) is also known to suppress adipogenesis. In this study, we found that microsomal PGE(2) synthase (PGES)-1 (mPGES-1; PTGES1) acted as the PGES in adipocytes and that P...

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Detalles Bibliográficos
Autores principales: Fujimori, Ko, Yano, Mutsumi, Ueno, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436788/
https://www.ncbi.nlm.nih.gov/pubmed/22970288
http://dx.doi.org/10.1371/journal.pone.0044698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436788/
https://www.ncbi.nlm.nih.gov/pubmed/22970288
http://dx.doi.org/10.1371/journal.pone.0044698

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