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Improving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data

Motivation: Due to the high mutation rate of human immunodeficiency virus (HIV), drug-resistant-variants emerge frequently. Therefore, researchers are constantly searching for new ways to attack the virus. One new class of anti-HIV drugs is the class of coreceptor antagonists that block cell entry b...

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Detalles Bibliográficos
Autores principales: Pfeifer, Nico, Lengauer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436800/
https://www.ncbi.nlm.nih.gov/pubmed/22962486
http://dx.doi.org/10.1093/bioinformatics/bts373