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Relating drug–protein interaction network with drug side effects

Motivation: Identifying the emergence and underlying mechanisms of drug side effects is a challenging task in the drug development process. This underscores the importance of system–wide approaches for linking different scales of drug actions; namely drug-protein interactions (molecular scale) and s...

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Detalles Bibliográficos
Autores principales: Mizutani, Sayaka, Pauwels, Edouard, Stoven, Véronique, Goto, Susumu, Yamanishi, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436810/
https://www.ncbi.nlm.nih.gov/pubmed/22962476
http://dx.doi.org/10.1093/bioinformatics/bts383