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Random sampling of elementary flux modes in large-scale metabolic networks

Motivation: The description of a metabolic network in terms of elementary (flux) modes (EMs) provides an important framework for metabolic pathway analysis. However, their application to large networks has been hampered by the combinatorial explosion in the number of modes. In this work, we develop...

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Detalles Bibliográficos
Autores principales: Machado, Daniel, Soons, Zita, Patil, Kiran Raosaheb, Ferreira, Eugénio C., Rocha, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436828/
https://www.ncbi.nlm.nih.gov/pubmed/22962475
http://dx.doi.org/10.1093/bioinformatics/bts401