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Drug target prediction using adverse event report systems: a pharmacogenomic approach

Motivation: Unexpected drug activities derived from off-targets are usually undesired and harmful; however, they can occasionally be beneficial for different therapeutic indications. There are many uncharacterized drugs whose target proteins (including the primary target and off-targets) remain unkn...

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Detalles Bibliográficos
Autores principales: Takarabe, Masataka, Kotera, Masaaki, Nishimura, Yosuke, Goto, Susumu, Yamanishi, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436840/
https://www.ncbi.nlm.nih.gov/pubmed/22962489
http://dx.doi.org/10.1093/bioinformatics/bts413