Nicorandil Prevents Right Ventricular Remodeling by Inhibiting Apoptosis and Lowering Pressure Overload in Rats with Pulmonary Arterial Hypertension

BACKGROUND: Most of the deaths among patients with severe pulmonary arterial hypertension (PAH) are caused by progressive right ventricular (RV) pathological remodeling, dysfunction, and failure. Nicorandil can inhibit the development of PAH by reducing pulmonary artery pressure and RV hypertrophy....

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Detalles Bibliográficos
Autores principales: Zuo, Xiang-Rong, Wang, Qiang, Cao, Quan, Yu, Yan-Zhe, Wang, Hui, Bi, Li-Qing, Xie, Wei-Ping, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436887/
https://www.ncbi.nlm.nih.gov/pubmed/22970229
http://dx.doi.org/10.1371/journal.pone.0044485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436887/
https://www.ncbi.nlm.nih.gov/pubmed/22970229
http://dx.doi.org/10.1371/journal.pone.0044485

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