Novel African Trypanocidal Agents: Membrane Rigidifying Peptides

The bloodstream developmental forms of pathogenic African trypanosomes are uniquely susceptible to killing by small hydrophobic peptides. Trypanocidal activity is conferred by peptide hydrophobicity and charge distribution and results from increased rigidity of the plasma membrane. Structural analys...

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Detalles Bibliográficos
Autores principales: Harrington, John M., Scelsi, Chris, Hartel, Andreas, Jones, Nicola G., Engstler, Markus, Capewell, Paul, MacLeod, Annette, Hajduk, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436892/
https://www.ncbi.nlm.nih.gov/pubmed/22970207
http://dx.doi.org/10.1371/journal.pone.0044384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436892/
https://www.ncbi.nlm.nih.gov/pubmed/22970207
http://dx.doi.org/10.1371/journal.pone.0044384

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