Late-onset Parkinsonism in NFκB/c-Rel-deficient mice

Activation of the nuclear factor κB/c-Rel can increase neuronal resilience to pathological noxae by regulating the expression of pro-survival manganese superoxide dismutase (MnSOD, now known as SOD2) and Bcl-xL genes. We show here that c-Rel-deficient (c-rel(−/−)) mice developed a Parkinson’s diseas...

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Detalles Bibliográficos
Autores principales: Baiguera, Cristina, Alghisi, Manuela, Pinna, Annalisa, Bellucci, Arianna, De Luca, Maria Antonietta, Frau, Lucia, Morelli, Micaela, Ingrassia, Rosaria, Benarese, Marina, Porrini, Vanessa, Pellitteri, Michele, Bertini, Giuseppe, Fabene, Paolo Francesco, Sigala, Sandra, Spillantini, Maria Grazia, Liou, Hsiou-Chi, Spano, Pier Franco, Pizzi, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437025/
https://www.ncbi.nlm.nih.gov/pubmed/22915735
http://dx.doi.org/10.1093/brain/aws193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437025/
https://www.ncbi.nlm.nih.gov/pubmed/22915735
http://dx.doi.org/10.1093/brain/aws193

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