PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice

Clinical trials in Parkinson’s disease have shown that transplants of embryonic mesencephalic dopamine neurons form new functional connections within the host striatum, but the therapeutic benefits have been highly variable. One obstacle has been poor survival and integration of grafted dopamine neu...

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Detalles Bibliográficos
Autores principales: Zhang, YaJun, Granholm, Ann-Charlotte, Huh, Kyounghee, Shan, Lufei, Diaz-Ruiz, Oscar, Malik, Nasir, Olson, Lars, Hoffer, Barry J., Lupica, Carl R., Hoffman, Alexander F., Bäckman, Cristina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437026/
https://www.ncbi.nlm.nih.gov/pubmed/22961549
http://dx.doi.org/10.1093/brain/aws196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437026/
https://www.ncbi.nlm.nih.gov/pubmed/22961549
http://dx.doi.org/10.1093/brain/aws196

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