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A semi-quantitative assay of overall DNA methylation status using Methyl-CpG binding protein (MBD1)
BACKGROUND: In mammals, DNA methylation at the 5-position of cytosine is the most essential epigenetic modification. Changes in the level of genome-wide DNA methylation (also known as overall DNA methylation) are associated with alterations in gene expression, thereby contributing to the phenotypic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437204/ https://www.ncbi.nlm.nih.gov/pubmed/22583687 http://dx.doi.org/10.1186/1756-0500-5-234 |