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Are Systemic Voriconazole and Caspofungin Ototoxic? An Experimental Study with Rats

OBJECTIVES: To determine whether systemic administration of voriconazole and caspofungin causes ototoxicity. METHODS: This study was conducted on 32 healthy male Wistar albino rats. The baseline auditory brainstem response (ABR) thresholds of all animals were obtained under general anesthesia. Then,...

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Detalles Bibliográficos
Autores principales: Aydın, Emine, Aydoğan, Filiz, Taştan, Eren, İriz, Ayşe, Karaca, Gökhan, Haberal Can, İlknur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437415/
https://www.ncbi.nlm.nih.gov/pubmed/22977711
http://dx.doi.org/10.3342/ceo.2012.5.3.145