Phorbol 12-Myristate 13-Acetate Induces MUC16 Expression via PKCδ and p38 in Human Airway Epithelial Cells

OBJECTIVES: Phorbol 12-myristate 13-acetate (PMA) is widely used as a protein kinase C (PKC) activator, PKC is involved in the secretion of mucins. MUC16, one of the membrane-bound mucins, is produced in human airway epithelial cells. However, the effect and signaling pathway of PMA on MUC16 express...

Descripción completa

Detalles Bibliográficos
Autores principales: Bae, Chang Hoon, Kim, Hak Soo, Song, Si-Youn, Kim, Yong-Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437418/
https://www.ncbi.nlm.nih.gov/pubmed/22977714
http://dx.doi.org/10.3342/ceo.2012.5.3.161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437418/
https://www.ncbi.nlm.nih.gov/pubmed/22977714
http://dx.doi.org/10.3342/ceo.2012.5.3.161

Ejemplares similares