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Phorbol 12-Myristate 13-Acetate Induces MUC16 Expression via PKCδ and p38 in Human Airway Epithelial Cells

OBJECTIVES: Phorbol 12-myristate 13-acetate (PMA) is widely used as a protein kinase C (PKC) activator, PKC is involved in the secretion of mucins. MUC16, one of the membrane-bound mucins, is produced in human airway epithelial cells. However, the effect and signaling pathway of PMA on MUC16 express...

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Detalles Bibliográficos
Autores principales:	Bae, Chang Hoon, Kim, Hak Soo, Song, Si-Youn, Kim, Yong-Dae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Otorhinolaryngology-Head and Neck Surgery 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437418/ https://www.ncbi.nlm.nih.gov/pubmed/22977714 http://dx.doi.org/10.3342/ceo.2012.5.3.161

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