Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan

While it is generally recognized that misfolding of specific proteins can cause late-onset disease, the contribution of protein aggregation to the normal aging process is less well understood. To address this issue, a mass spectrometry-based proteomic analysis was performed to identify proteins that...

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Detalles Bibliográficos
Autores principales: Reis-Rodrigues, Pedro, Czerwieniec, Gregg, Peters, Theodore W, Evani, Uday S, Alavez, Silvestre, Gaman, Emily A, Vantipalli, Maithili, Mooney, Sean D, Gibson, Bradford W, Lithgow, Gordon J, Hughes, Robert E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437485/
https://www.ncbi.nlm.nih.gov/pubmed/22103665
http://dx.doi.org/10.1111/j.1474-9726.2011.00765.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437485/
https://www.ncbi.nlm.nih.gov/pubmed/22103665
http://dx.doi.org/10.1111/j.1474-9726.2011.00765.x

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