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Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan
While it is generally recognized that misfolding of specific proteins can cause late-onset disease, the contribution of protein aggregation to the normal aging process is less well understood. To address this issue, a mass spectrometry-based proteomic analysis was performed to identify proteins that...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437485/ https://www.ncbi.nlm.nih.gov/pubmed/22103665 http://dx.doi.org/10.1111/j.1474-9726.2011.00765.x |