Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate

BACKGROUND AND PURPOSE: Choline analogues, a new type of antimalarials, exert potent in vitro and in vivo antimalarial activity. This has given rise to albitiazolium, which is currently in phase II clinical trials to cure severe malaria. Here we dissected its mechanism of action step by step from ch...

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Detalles Bibliográficos
Autores principales: Wein, S, Maynadier, M, Bordat, Y, Perez, J, Maheshwari, S, Bette-Bobillo, P, Tran Van Ba, C, Penarete-Vargas, D, Fraisse, L, Cerdan, R, Vial, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437492/
https://www.ncbi.nlm.nih.gov/pubmed/22471905
http://dx.doi.org/10.1111/j.1476-5381.2012.01966.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437492/
https://www.ncbi.nlm.nih.gov/pubmed/22471905
http://dx.doi.org/10.1111/j.1476-5381.2012.01966.x

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