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The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase

In muscle, aging is associated with a failure of adaptive responses to contractile activity, and this is hypothesized to play an important role in age-related loss of muscle mass and function. Mice lacking the Cu,Zn superoxide dismutase (Cu,ZnSOD, SOD1) show an accelerated, age-related loss of muscl...

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Detalles Bibliográficos
Autores principales: Vasilaki, Aphrodite, van der Meulen, Jack H, Larkin, Lisa, Harrison, Dawn C, Pearson, Timothy, Van Remmen, Holly, Richardson, Arlan, Brooks, Susan V, Jackson, Malcolm J, McArdle, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437493/
https://www.ncbi.nlm.nih.gov/pubmed/20883524
http://dx.doi.org/10.1111/j.1474-9726.2010.00635.x