Nanog Is the Gateway to the Pluripotent Ground State

Pluripotency is generated naturally during mammalian development through formation of the epiblast, founder tissue of the embryo proper. Pluripotency can be recreated by somatic cell reprogramming. Here we present evidence that the homeodomain protein Nanog mediates acquisition of both embryonic and...

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Detalles Bibliográficos
Autores principales: Silva, Jose, Nichols, Jennifer, Theunissen, Thorold W., Guo, Ge, van Oosten, Anouk L., Barrandon, Ornella, Wray, Jason, Yamanaka, Shinya, Chambers, Ian, Smith, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437554/
https://www.ncbi.nlm.nih.gov/pubmed/19703398
http://dx.doi.org/10.1016/j.cell.2009.07.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437554/
https://www.ncbi.nlm.nih.gov/pubmed/19703398
http://dx.doi.org/10.1016/j.cell.2009.07.039

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