N-Amino-imidazolin-2-one Peptide Mimic Synthesis and Conformational Analysis

[Image: see text] Base-promoted 5-exo-dig cyclizations of aza-propargylglycinamides provided N-amino-imidazolin-2-one peptide mimics, which exhibited turn geometry in X-ray crystallographic and NMR spectroscopic analyses. Sonogashira coupling prior to cyclization afforded N-amino-imidazolin-2-ones w...

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Detalles Bibliográficos
Autores principales: Proulx, Caroline, Lubell, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437692/
https://www.ncbi.nlm.nih.gov/pubmed/22892053
http://dx.doi.org/10.1021/ol302021n

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437692/
https://www.ncbi.nlm.nih.gov/pubmed/22892053
http://dx.doi.org/10.1021/ol302021n

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