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Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells

It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells. Using bioinformatics analysis and functional screening, we screened short-activating RNA (saRNA) oligonucleotides designed to target the promoter re...

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Detalles Bibliográficos
Autores principales: Voutila, Jon, Sætrom, Pål, Mintz, Paul, Sun, Guihua, Alluin, Jessica, Rossi, John J, Habib, Nagy A, Kasahara, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437803/
https://www.ncbi.nlm.nih.gov/pubmed/23344177
http://dx.doi.org/10.1038/mtna.2012.20