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Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy

MicroRNAs (miRNAs) are a class of small RNAs that regulate gene expression and are implicated in wide-ranging cellular processes and pathological conditions including Duchenne muscular dystrophy (DMD). We have compared differential miRNA expression in proximal and distal limb muscles, diaphragm, hea...

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Detalles Bibliográficos
Autores principales: Roberts, Thomas C, Blomberg, K Emelie M, McClorey, Graham, Andaloussi, Samir EL, Godfrey, Caroline, Betts, Corinne, Coursindel, Thibault, Gait, Michael J, Edvard Smith, CI, Wood, Matthew JA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437806/
https://www.ncbi.nlm.nih.gov/pubmed/23344181
http://dx.doi.org/10.1038/mtna.2012.26