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Clinical potential of sodium-glucose cotransporter 2 inhibitors in the management of type 2 diabetes

BACKGROUND: The kidney plays an important role in glucose metabolism, and has been considered a target for therapeutic intervention. The sodium-glucose cotransporter type 2 (SGLT2) mediates most of the glucose reabsorption from the proximal renal tubule. Inhibition of SGLT2 leads to glucosuria and p...

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Detalles Bibliográficos
Autores principales: Kim, Yoojin, Babu, Ambika R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437808/
https://www.ncbi.nlm.nih.gov/pubmed/22977310
http://dx.doi.org/10.2147/DMSO.S22545