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Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis

Correct tissue architecture is essential for normal physiology, yet there have been few attempts to recreate tissues using micro-patterning. We have used polymer brush micro-engineering to generate a stratified micro-epidermis with fewer than 10 human keratinocytes. Epidermal stem cells are captured...

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Detalles Bibliográficos
Autores principales: Gautrot, Julien E., Wang, Chunming, Liu, Xin, Goldie, Stephen J., Trappmann, Britta, Huck, Wilhelm T.S., Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437971/
https://www.ncbi.nlm.nih.gov/pubmed/22541538
http://dx.doi.org/10.1016/j.biomaterials.2012.04.009