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Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis
Correct tissue architecture is essential for normal physiology, yet there have been few attempts to recreate tissues using micro-patterning. We have used polymer brush micro-engineering to generate a stratified micro-epidermis with fewer than 10 human keratinocytes. Epidermal stem cells are captured...
Autores principales: | Gautrot, Julien E., Wang, Chunming, Liu, Xin, Goldie, Stephen J., Trappmann, Britta, Huck, Wilhelm T.S., Watt, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437971/ https://www.ncbi.nlm.nih.gov/pubmed/22541538 http://dx.doi.org/10.1016/j.biomaterials.2012.04.009 |
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