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Direct visualization of specifically modified extracellular glycans in living animals

Modification patterns of the extracellular glycan heparan sulfate coordinate protein function in metazoans, yet in vivo imaging of such non-genetically encoded structures has been impossible. Here we report a transgenic method in Caenorhabditis elegans that allows direct live imaging of specific hep...

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Detalles Bibliográficos
Autores principales: Attreed, Matthew, Desbois, Muriel, van Kuppevelt, Toin H., Bülow, Hannes E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437987/
https://www.ncbi.nlm.nih.gov/pubmed/22466794
http://dx.doi.org/10.1038/nmeth.1945