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Direct visualization of specifically modified extracellular glycans in living animals
Modification patterns of the extracellular glycan heparan sulfate coordinate protein function in metazoans, yet in vivo imaging of such non-genetically encoded structures has been impossible. Here we report a transgenic method in Caenorhabditis elegans that allows direct live imaging of specific hep...
Autores principales: | Attreed, Matthew, Desbois, Muriel, van Kuppevelt, Toin H., Bülow, Hannes E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437987/ https://www.ncbi.nlm.nih.gov/pubmed/22466794 http://dx.doi.org/10.1038/nmeth.1945 |
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