A genome-wide screen in human embryonic stem cells reveals novel sites of allele-specific histone modification associated with known disease loci

BACKGROUND: Chromatin structure at a given site can differ between chromosome copies in a cell, and such imbalances in chromatin structure have been shown to be important in understanding the molecular mechanisms controlling several disease loci. Human genetic variation, DNA methylation, and disease...

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Detalles Bibliográficos
Autores principales: Prendergast, James G D, Tong, Pin, Hay, David C, Farrington, Susan M, Semple, Colin A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438052/
https://www.ncbi.nlm.nih.gov/pubmed/22607690
http://dx.doi.org/10.1186/1756-8935-5-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438052/
https://www.ncbi.nlm.nih.gov/pubmed/22607690
http://dx.doi.org/10.1186/1756-8935-5-6

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