A genome-wide screen in human embryonic stem cells reveals novel sites of allele-specific histone modification associated with known disease loci

BACKGROUND: Chromatin structure at a given site can differ between chromosome copies in a cell, and such imbalances in chromatin structure have been shown to be important in understanding the molecular mechanisms controlling several disease loci. Human genetic variation, DNA methylation, and disease...

Descripción completa

Detalles Bibliográficos
Autores principales: Prendergast, James G D, Tong, Pin, Hay, David C, Farrington, Susan M, Semple, Colin A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438052/
https://www.ncbi.nlm.nih.gov/pubmed/22607690
http://dx.doi.org/10.1186/1756-8935-5-6

Ejemplares similares

Ejemplares similares