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Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach

BACKGROUND: Malawi commenced the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) into the routine infant immunisation schedule in November 2011. Here we have tested the utility of high throughput whole genome sequencing to provide a high-resolution view of pre-vaccine pneumococc...

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Detalles Bibliográficos
Autores principales: Everett, Dean B., Cornick, Jennifer, Denis, Brigitte, Chewapreecha, Claire, Croucher, Nicholas, Harris, Simon, Parkhill, Julian, Gordon, Stephen, Carrol, Enitan D., French, Neil, Heyderman, Robert S., Bentley, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438182/
https://www.ncbi.nlm.nih.gov/pubmed/22970189
http://dx.doi.org/10.1371/journal.pone.0044250