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Estrogen Deficiency Induces the Differentiation of IL-17 Secreting Th17 Cells: A New Candidate in the Pathogenesis of Osteoporosis

Th17 cells produce IL-17, and the latter promotes bone loss in collagen-induced arthritis in mice. Blocking IL-17 action in mouse model of rheumatoid arthritis reduces disease symptoms. These observations suggest that Th17 cells may be involved in the pathogenesis of bone loss. However, the role of...

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Detalles Bibliográficos
Autores principales: Tyagi, Abdul M., Srivastava, Kamini, Mansoori, Mohd Nizam, Trivedi, Ritu, Chattopadhyay, Naibedya, Singh, Divya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438183/
https://www.ncbi.nlm.nih.gov/pubmed/22970248
http://dx.doi.org/10.1371/journal.pone.0044552