Expression of MUC17 Is Regulated by HIF1α-Mediated Hypoxic Responses and Requires a Methylation-Free Hypoxia Responsible Element in Pancreatic Cancer

MUC17 is a type 1 membrane-bound glycoprotein that is mainly expressed in the digestive tract. Recent studies have demonstrated that the aberrant overexpression of MUC17 is correlated with the malignant potential of pancreatic ductal adenocarcinomas (PDACs); however, the exact regulatory mechanism o...

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Detalles Bibliográficos
Autores principales: Kitamoto, Sho, Yokoyama, Seiya, Higashi, Michiyo, Yamada, Norishige, Matsubara, Shyuichiro, Takao, Sonshin, Batra, Surinder K., Yonezawa, Suguru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438193/
https://www.ncbi.nlm.nih.gov/pubmed/22970168
http://dx.doi.org/10.1371/journal.pone.0044108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438193/
https://www.ncbi.nlm.nih.gov/pubmed/22970168
http://dx.doi.org/10.1371/journal.pone.0044108

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