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Enhanced Periosteal and Endocortical Responses to Axial Tibial Compression Loading in Conditional Connexin43 Deficient Mice

The gap junction protein, connexin43 (Cx43) is involved in mechanotransduction in bone. Recent studies using in vivo models of conditional Cx43 gene (Gja1) deletion in the osteogenic linage have generated inconsistent results, with Gja1 ablation resulting in either attenuated or enhanced response to...

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Detalles Bibliográficos
Autores principales: Grimston, Susan K., Watkins, Marcus P., Brodt, Michael D., Silva, Matthew J., Civitelli, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438198/
https://www.ncbi.nlm.nih.gov/pubmed/22970183
http://dx.doi.org/10.1371/journal.pone.0044222