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Simvastatin and Losartan Differentially and Synergistically Inhibit Atherosclerosis in Apolipoprotein E(-/-) Mice

BACKGROUND AND OBJECTIVES: Since statins and angiotensin receptor blockers are a frequently prescribed combination in patients with atherosclerotic cardiovascular diseases, we tested the interactive effects of simvastatin and losartan on atherosclerosis in apolipoprotein E (apoE)(-/-) mice. MATERIAL...

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Detalles Bibliográficos
Autores principales: Lee, Bok-Soo, Choi, Jin Yong, Kim, Joo Yun, Han, Seul Hee, Park, Jeong Euy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Cardiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438264/
https://www.ncbi.nlm.nih.gov/pubmed/22977450
http://dx.doi.org/10.4070/kcj.2012.42.8.543