Prolyl isomerase Pin1 down-regulates tumor suppressor RUNX3 in breast cancer

Emerging evidence demonstrates that RUNX3 is a tumor suppressor in breast cancer. Inactivation of RUNX3 in mice results in spontaneous mammary gland tumors, and decreased or silenced expression of RUNX3 is frequently found in breast cancer cell lines and human breast cancer samples. However, the und...

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Detalles Bibliográficos
Autores principales: Tsang, Ying-Hung Nicole, Wu, Xue-Wei, Lim, Jing-Shan, Ong, Chee Wee, Salto-Tellez, Manuel, Ito, Kosei, Ito, Yoshiaki, Chen, Lin-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438320/
https://www.ncbi.nlm.nih.gov/pubmed/22580604
http://dx.doi.org/10.1038/onc.2012.178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438320/
https://www.ncbi.nlm.nih.gov/pubmed/22580604
http://dx.doi.org/10.1038/onc.2012.178

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