Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

Temporal lobe epilepsy is a common, chronic neurologic disorder characterized by recurrent spontaneous seizures. MicroRNAs (miRNAs) are small, non-coding RNAs that regulate post-transcriptional expression of protein-coding mRNAs, which may have important roles in the pathogenesis of neurologic disor...

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Detalles Bibliográficos
Autores principales: Jimenez-Mateos, Eva M., Engel, Tobias, Merino-Serrais, Paula, McKiernan, Ross C., Tanaka, Katsuhiro, Mouri, Genshin, Sano, Takanori, O’Tuathaigh, Colm, Waddington, John L., Prenter, Suzanne, Delanty, Norman, Farrell, Michael A., O’Brien, Donncha F., Conroy, Ronán M., Stallings, Raymond L., deFelipe, Javier, Henshall, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438344/
https://www.ncbi.nlm.nih.gov/pubmed/22683779
http://dx.doi.org/10.1038/nm.2834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438344/
https://www.ncbi.nlm.nih.gov/pubmed/22683779
http://dx.doi.org/10.1038/nm.2834

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