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Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia

Although the treatment of acute myeloid leukemia (AML) has improved significantly, more than half of all patients develop disease that is refractory to intensive chemotherapy(1,2). Functional genomics approaches offer a means to discover specific molecules mediating aberrant growth and survival of c...

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Detalles Bibliográficos
Autores principales: Kentsis, Alex, Reed, Casie, Rice, Kim L., Sanda, Takaomi, Rodig, Scott J., Tholouli, Eleni, Christie, Amanda, Valk, Peter J.M., Delwel, Ruud, Ngo, Vu, Kutok, Jeffery L., Dahlberg, Suzanne E., Moreau, Lisa A., Byers, Richard J., Christensen, James G., Woude, George Vande, Licht, Jonathan D., Kung, Andrew L., Staudt, Louis M., Look, A. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438345/
https://www.ncbi.nlm.nih.gov/pubmed/22683780
http://dx.doi.org/10.1038/nm.2819