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Fingolimod in the treatment algorithm of relapsing remitting multiple sclerosis: a statement of the Central and East European (CEE) MS Expert Group
Fingolimod is the first oral treatment of multiple sclerosis. It is the first-in-class sphingosine 1-phosphate receptor modulator that binds to sphingosine 1-phophate receptors on lymphocytes and via downregulation of the receptor prevents lymphocyte egress from lymphoid tissues into the circulation...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer-Verlag
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438392/ https://www.ncbi.nlm.nih.gov/pubmed/22895849 http://dx.doi.org/10.1007/s10354-012-0123-y |