Cysteinyl leukotriene signaling through perinuclear CysLT(1) receptors on vascular smooth muscle cells transduces nuclear calcium signaling and alterations of gene expression

Leukotrienes are pro-inflammatory mediators that are locally produced in coronary atherosclerotic plaques. The response induced by cysteinyl leukotrienes (CysLT) in human coronary arteries may be altered under pathological conditions, such as atherosclerosis. The aim of the present study was to eluc...

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Detalles Bibliográficos
Autores principales: Eaton, Alison, Nagy, Edit, Pacault, Mathilde, Fauconnier, Jérémy, Bäck, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438394/
https://www.ncbi.nlm.nih.gov/pubmed/22527886
http://dx.doi.org/10.1007/s00109-012-0904-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438394/
https://www.ncbi.nlm.nih.gov/pubmed/22527886
http://dx.doi.org/10.1007/s00109-012-0904-1

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