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Analysis of region-specific changes in gene expression upon treatment with citalopram and desipramine reveals temporal dynamics in response to antidepressant drugs at the transcriptome level

RATIONALE: The notion that the onset of action of antidepressant drugs (ADs) takes weeks is widely accepted; however, the sequence of events necessary for therapeutic effects still remains obscure. OBJECTIVE: We aimed to evaluate a time-course of ADs-induced alterations in the expression of 95 selec...

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Detalles Bibliográficos
Autores principales: Gąska, Magdalena, Kuśmider, Maciej, Solich, Joanna, Faron-Górecka, Agata, Krawczyk, Małgorzata J., Kułakowski, Krzysztof, Dziedzicka-Wasylewska, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438400/
https://www.ncbi.nlm.nih.gov/pubmed/22547330
http://dx.doi.org/10.1007/s00213-012-2714-0