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Varenicline decreases alcohol consumption in heavy-drinking smokers

RATIONALE: Emerging evidence suggests that the α4β2 form of the nicotinic acetylcholine receptor (nAChR) modulates the rewarding effects of alcohol. The nAChR α4β2 subunit partial agonist varenicline (Chantix™), which is approved by the Food and Drug Administration for smoking cessation, also decrea...

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Detalles Bibliográficos
Autores principales: Mitchell, Jennifer M., Teague, Candice H., Kayser, Andrew S., Bartlett, Selena E., Fields, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438402/
https://www.ncbi.nlm.nih.gov/pubmed/22547331
http://dx.doi.org/10.1007/s00213-012-2717-x