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(1)H, (15)N and (13)C backbone resonance assignments of the archetypal serpin α(1)-antitrypsin
Alpha(1)-antitrypsin is a 45-kDa (394-residue) serine protease inhibitor synthesized by hepatocytes, which is released into the circulatory system and protects the lung from the actions of neutrophil elastase via a conformational transition within a dynamic inhibitory mechanism. Relatively common po...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438405/ https://www.ncbi.nlm.nih.gov/pubmed/22109101 http://dx.doi.org/10.1007/s12104-011-9345-y |