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(1)H, (15)N and (13)C backbone resonance assignments of the archetypal serpin α(1)-antitrypsin

Alpha(1)-antitrypsin is a 45-kDa (394-residue) serine protease inhibitor synthesized by hepatocytes, which is released into the circulatory system and protects the lung from the actions of neutrophil elastase via a conformational transition within a dynamic inhibitory mechanism. Relatively common po...

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Detalles Bibliográficos
Autores principales: Nyon, Mun Peak, Kirkpatrick, John, Cabrita, Lisa D., Christodoulou, John, Gooptu, Bibek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438405/
https://www.ncbi.nlm.nih.gov/pubmed/22109101
http://dx.doi.org/10.1007/s12104-011-9345-y