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Imaging the neural correlates of neuropathic pain and pleasurable relief associated with inherited erythromelalgia in a single subject with quantitative arterial spin labelling

We identified a patient with severe inherited erythromelalgia secondary to an L858F mutation in the voltage-gated sodium channel Na(v)1.7. The patient reported severe ongoing foot pain, which was exquisitely sensitive to limb cooling. We confirmed this heat hypersensitivity using quantitative sensor...

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Detalles Bibliográficos
Autores principales: Segerdahl, Andrew R., Xie, Jingyi, Paterson, Kathryn, Ramirez, Juan D., Tracey, Irene, Bennett, David L.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438450/
https://www.ncbi.nlm.nih.gov/pubmed/22365309
http://dx.doi.org/10.1016/j.pain.2011.12.012