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Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes

Fibroblastic reticular cells (FRC) form the structural backbone of the T cell rich zones in secondary lymphoid organs (SLO), but also actively influence the adaptive immune response. They provide a guidance path for immigrating T lymphocytes and dendritic cells (DC) and are the main local source of...

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Detalles Bibliográficos
Autores principales: Siegert, Stefanie, Luther, Sanjiv A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438460/
https://www.ncbi.nlm.nih.gov/pubmed/22973278
http://dx.doi.org/10.3389/fimmu.2012.00285